• Help people with EB

    Your support of DEBRA International or a national EB group enables us to provide the best quality of life for families and individuals affected by EB.

Donation Account: IBAN AT65 6000 0005 1004 5254, BIC BAWAATWW, DEBRA International, Am Heumarkt 27/1, 1030 Vienna

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Research priorities and fields


DEBRA International funds peer-reviewed research across a broad spectrum, from improving our fundamental understanding of the disease – which itself can lead to novel treatment approaches – as well as advanced preclinical research which focuses on safety and likely efficacy of candidate therapies before clinical trials in patients.

Research priorities reflect our wish to provide benefit to those living with EB at
present, and those in generations to come. DEBRA therefore balances support for research aimed at symptom relief and to deliver near-term benefits to patients ('clinical research'), and support for research which will deliver, probably in the longer-term, cures or therapies that have a step-change impact in improving the natural course of the condition, and are safer, more effective, and more patient-friendly.

To achieve our goals of improved treatments for patients and, ultimately, cures for EB, DEBRA International must stay focused on key research priorities. With advances in scientific knowledge, and developments in technology, new opportunities present themselves. Our strategy for research is to take advantage of these opportunities as they arise, and so the portfolio of research that we fund continues to evolve. Equal support is given to research which, it is hoped, will provide benefit in the near-term to people currently living with EB, and research which, possibly over the longer term, will yield cures, and improved treatments, diagnostics and prognostics.


DEBRA International's current research priorities

  • Improve our understanding of the biology and genetics of all forms of EB, as better understanding can lead to new approaches to diagnose and treat EB
  • Work towards the development of therapies (including possible gene-therapies, cell-therapies, drug therapies or protein therapies)
  • Understand the nature of wound healing and the development of skin cancer in EB, and seek to develop better treatments and prevention strategies
  • Support clinical-care research to improve the management of EB through symptom relief